MolNFT v1 · #187756 · protein

Atomic model of prestin from gerbil (meriones unguiculatus)

7SUN · Prestin, enhanced yellow fluorescent protein chimera: “Atomic model of prestin from gerbil (meriones unguiculatus)”. Electron microscopy, 20 pockets (best druggability 0.83). MolNFT v1 #187756 on GenesisL1: 3D structure, binding…

PDB: 7SUN
Type: protein
Length: 1,350 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Prestin, enhanced yellow fluorescent protein chimera
UniProt: Q9JKQ2
Pockets: 20 · best druggability 0.83

Structure

electron microscopy · 1 distinct chain · 62% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Prestin, enhanced yellow fluorescent protein chimera	protein	675	62% helix, 6% strand	Q9JKQ2

Pockets

20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	666	0.83	0.87	80	empty
2	170	0.68	0.88	36	empty
3	178	0.66	0.86	36	empty
4	450	0.65	0.78	59	empty
5	376	0.65	0.79	45	empty

Interfaces

1 interface between chains.

A–B · 4051 Å² buried · 49 hydrogen bonds · protein-protein

Compared structures

7SUN · Atomic model of prestin from gerbil (Meriones unguiculatus) · the same entry in another collection · chain A against A, TM-score 1.00
Q9JKQ2 · AlphaFold monomer V2.0 prediction for prestin (Q9JKQ2) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9JKQ2
Elsewhere: RCSB PDB 7SUN · PDBe 7SUN · UniProt Q9JKQ2

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