MolNFT v1 · #187711 · protein

Crystal structure of human sting R232 in complex with compound 11

7SSM · Stimulator of interferon genes protein: “Crystal structure of human sting R232 in complex with compound 11”. X-ray diffraction, 1 ligand (B7L), 1 pocket (best druggability 0.35). MolNFT v1 #187711 on GenesisL1: 3D structure, binding…

PDB: 7SSM
Type: protein
Length: 169 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Stimulator of interferon genes protein
UniProt: A0A2R3XZB7
Ligands: B7L
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Stimulator of interferon genes protein	protein	169	44% helix, 30% strand	A0A2R3XZB7

Ligands and binding sites

B7L · 2-({[(8R)-pyrazolo[1,5-a]pyrimidine-3-carbonyl]amino}methyl)-1-benzofuran-7-carboxylic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	105	0.35	0.73	17	empty

Compared structures

7SSM · Crystal structure of human STING R232 in complex with compound 11 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A2R3XZB7
Elsewhere: RCSB PDB 7SSM · PDBe 7SSM · UniProt A0A2R3XZB7

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