MolNFT v1 · #187690 · protein

Cryo-EM structure of the seam subunits of the enteropathogenic E. COLI O127:H6 flagellar filament

7SQJ · Flagellin: “Cryo-EM structure of the seam subunits of the enteropathogenic E. COLI O127:H6 flagellar filament”. Electron microscopy, 9 pockets (best druggability 0.71). MolNFT v1 #187690 on GenesisL1: 3D structure, binding sites and…

PDB: 7SQJ
Type: protein
Length: 1,092 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flagellin
UniProt: B7USU2
Pockets: 9 · best druggability 0.71

Structure

electron microscopy · 1 distinct chain · 40% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Flagellin	protein	546	40% helix, 13% strand	B7USU2

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	95	0.71	0.94	28	empty
2	133	0.55	0.82	23	empty
3	159	0.47	0.76	35	empty
4	130	0.44	0.77	24	empty
5	156	0.41	0.74	28	empty

Interfaces

1 interface between chains.

A–B · 2143 Å² buried · 21 hydrogen bonds · protein-protein

Compared structures

7SQJ · Cryo-EM structure of the seam subunits of the enteropathogenic E. coli O127:H6 flagellar… · the same entry in another collection · chain A against A, TM-score 1.00
B7USU2 · AlphaFold monomer V2.0 prediction for flagellin (B7USU2) · a predicted model of the same protein · chain A against A, TM-score 0.55

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B7USU2
Elsewhere: RCSB PDB 7SQJ · PDBe 7SQJ · UniProt B7USU2

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