MolNFT v1 · #18769 · protein

T.GONDII LDH1 apo form

1PZE · Lactate dehydrogenase: “T.GONDII LDH1 apo form”. X-ray diffraction, 5 pockets (best druggability 0.73). MolNFT v1 #18769 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1PZE
Type: protein
Length: 323 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lactate dehydrogenase
EC: 1.1.1.27
UniProt: P90613
Pockets: 5 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lactate dehydrogenase (EC 1.1.1.27)	protein	323	50% helix, 20% strand	P90613

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	326	0.73	0.85	50	empty
2	124	0.55	0.82	25	empty
3	153	0.45	0.76	20	empty
4	78	0.33	0.75	14	empty
5	73	0.28	0.72	20	empty

Compared structures

1PZE · T.gondii LDH1 apo form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P90613
Elsewhere: RCSB PDB 1PZE · PDBe 1PZE · UniProt P90613

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