MolNFT v1 · #187677 · protein
Nucleotide-free GET3 in two open forms
7SPZ · ATPase ASNA1 homolog: “Nucleotide-free GET3 in two open forms”. X-ray diffraction, 1 ligand (ZN), 7 pockets (best druggability 0.50). MolNFT v1 #187677 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SPZ
- Type
- protein
- Length
- 641 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATPase ASNA1 homolog
- EC
- 3.6.-.-
- UniProt
- A8B3G9
- Ligands
- ZN
- Pockets
- 7 · best druggability 0.50
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATPase ASNA1 homolog (EC 3.6.-.-) | protein | 328 | 49% helix, 15% strand | A8B3G9 |
| B | ATPase ASNA1 homolog (EC 3.6.-.-) | protein | 313 | 50% helix, 13% strand | A8B3G9 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 172 | 0.50 | 0.77 | 32 | empty |
| 2 | 148 | 0.47 | 0.77 | 25 | empty |
| 3 | 121 | 0.46 | 0.78 | 24 | empty |
| 4 | 175 | 0.45 | 0.75 | 16 | empty |
| 5 | 66 | 0.43 | 0.82 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 75 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8B3G9
- Elsewhere: RCSB PDB 7SPZ · PDBe 7SPZ · UniProt A8B3G9
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