MolNFT v1 · #187572 · protein
Crystal structure of measles virus matrix protein
7SKS: “Crystal structure of measles virus matrix protein”. X-ray diffraction, 11 pockets (best druggability 0.64). MolNFT v1 #187572 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SKS
- Type
- protein
- Length
- 553 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Matrix protein
- UniProt
- Q9W850
- Pockets
- 11 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 19% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Matrix protein | protein | 271 | 20% helix, 45% strand | Q9W850 |
| B | Matrix protein | protein | 282 | 19% helix, 45% strand | Q9W850 |
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 398 | 0.64 | 0.78 | 53 | empty |
| 2 | 135 | 0.57 | 0.83 | 25 | empty |
| 3 | 108 | 0.53 | 0.82 | 18 | empty |
| 4 | 92 | 0.52 | 0.83 | 17 | empty |
| 5 | 94 | 0.52 | 0.83 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 2378 Ų buried · 53 hydrogen bonds · protein-protein
Compared structures
- 7SKS · Crystal structure of measles virus matrix protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9W850
- Elsewhere: RCSB PDB 7SKS · PDBe 7SKS · UniProt Q9W850
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