MolNFT v1 · #187533 · protein
Crystal structure of udp-N-acetylmuramoylalanine-D-glutamate ligase from acinetobacter baumannii AB5075-uw
7SIR · Udp-N-acetylmuramoylalanine--D-glutamate ligase: “Crystal structure of udp-N-acetylmuramoylalanine-D-glutamate ligase from acinetobacter baumannii AB5075-uw”. X-ray diffraction, 3 pockets (best druggability 0.49). MolNFT v1 #187533…
- PDB
- 7SIR
- Type
- protein
- Length
- 431 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Udp-N-acetylmuramoylalanine--D-glutamate ligase
- EC
- 6.3.2.9
- UniProt
- B7H1N2
- Pockets
- 3 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Udp-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) | protein | 431 | 37% helix, 23% strand | B7H1N2 |
Ligands and binding sites
- FMT · Formic acid · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 185 | 0.49 | 0.76 | 26 | empty |
| 2 | 56 | 0.42 | 0.83 | 15 | empty |
| 3 | 83 | 0.39 | 0.77 | 17 | empty |
Compared structures
- 7SIR · Crystal Structure of UDP-N-acetylmuramoylalanine-D-glutamate ligase from Acinetobacter… · the same entry in another collection · chain A against A, TM-score 1.00
- B7H1N2 · AlphaFold monomer V2.0 prediction for udp-N-acetylmuramoylalanine-- D-glutamate ligase… · a predicted model of the same protein · chain A against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7H1N2
- Elsewhere: RCSB PDB 7SIR · PDBe 7SIR · UniProt B7H1N2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.