MolNFT v1 · #187513 · protein
Apo-chrmine in MSP1E3D1 lipid nanodisc
7SHS: “Apo-chrmine in MSP1E3D1 lipid nanodisc”. Electron microscopy, 10 pockets (best druggability 0.86). MolNFT v1 #187513 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SHS
- Type
- protein
- Length
- 849 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chrmine
- Pockets
- 10 · best druggability 0.86
Structure
electron microscopy · 1 distinct chain · 69% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Chrmine | protein | 283 | 69% helix, 1% strand | — |
Pockets
10 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1182 | 0.86 | 0.87 | 134 | empty |
| 2 | 591 | 0.82 | 0.86 | 59 | empty |
| 3 | 620 | 0.82 | 0.86 | 61 | empty |
| 4 | 604 | 0.81 | 0.86 | 62 | empty |
| 5 | 394 | 0.80 | 0.88 | 56 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1540 Ų buried · 6 hydrogen bonds · protein-protein
- A–C · 1520 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 1468 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 7SHS · Apo-ChRmine in MSP1E3D1 lipid nanodisc · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7SHS · PDBe 7SHS
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