MolNFT v1 · #187487 · protein
Crystal structure of a Fab variant containing a fluorescent noncanonical amino acid with blocked excited state proton transfer and in complex with its antigen, CD40L
7SGM: “Crystal structure of a Fab variant containing a fluorescent noncanonical amino acid with blocked excited…”. X-ray diffraction, 2 ligands (TMO, NAG). MolNFT v1 #187487 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SGM
- Type
- protein
- Length
- 1,693 residues
- Chains
- 9
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P29965
- Ligands
- TMO, NAG
Structure
x-ray diffraction · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 137 | — | P29965 |
| B | — | protein | 140 | — | P29965 |
| C | — | protein | 137 | — | P29965 |
| H | — | protein | 211 | — | — |
| L | — | protein | 208 | — | — |
| K | — | protein | 213 | — | — |
| M | — | protein | 217 | — | — |
| X | — | protein | 214 | — | — |
| Y | — | protein | 216 | — | — |
Ligands and binding sites
- TMO · trimethylamine oxide · ligand · 3 copies · chains L, M, Y
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A, B, C
- PEG · Di(hydroxyethyl)ether · additive · 13 copies · chains A, B, C, H, L, K, M, X, Y
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7SGM · Crystal structure of a Fab variant containing a fluorescent noncanonical amino acid with… · the same entry in another collection · chain Y against Y, TM-score 1.00
- P29965 · AlphaFold monomer V2.0 prediction for CD40 ligand (P29965) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29965
- Elsewhere: RCSB PDB 7SGM · PDBe 7SGM · UniProt P29965
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