MolNFT v1 · #187445 · protein

Crystal structure of caspase-3 with peptide inhibitor ac-VDV(DAB)D-cho

7SEO: “Crystal structure of caspase-3 with peptide inhibitor ac-VDV(DAB)D-cho”. X-ray diffraction, 1 ligand (ACE). MolNFT v1 #187445 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7SEO
Type: protein
Length: 478 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P42574
Ligands: ACE

Structure

x-ray diffraction · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	142	—	P42574
B	—	protein	93	—	P42574
C	—	protein	141	—	P42574
D	—	protein	92	—	P42574
F, G	—	protein	5	—	—

Ligands and binding sites

ACE · Acetyl group · ligand · 2 copies · chains B, F, D, G

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7SEO · Crystal Structure of Caspase-3 with Peptide Inhibitor Ac-VDV(DAB)D-CHO · the same entry in another collection · chain G against G, TM-score 1.00
P42574 · AlphaFold monomer V2.0 prediction for caspase-3 (P42574) · a predicted model of the same protein · chain C against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P42574
Elsewhere: RCSB PDB 7SEO · PDBe 7SEO · UniProt P42574

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