MolNFT v1 · #187436 · protein
Structure of E. COLI letb delta (RING6) mutant, ring 1 in the open state (model 2, rings 1-3 only)
7SEF · Mce family protein, intermembrane transport protein yebt…: “Structure of E. COLI letb delta (RING6) mutant, ring 1 in the open state (model 2, rings 1-3 only)”. Electron microscopy, 20 pockets (best druggability 0.77). MolNFT v1…
- PDB
- 7SEF
- Type
- protein
- Length
- 2,256 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mce family protein, intermembrane transport protein yebt chimera
- UniProt
- A0A769F599
- Pockets
- 20 · best druggability 0.77
Structure
electron microscopy · 1 distinct chain · 9% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Mce family protein, intermembrane transport protein yebt chimera | protein | 376 | 9% helix, 37% strand | A0A769F599 |
Pockets
20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1197 | 0.77 | 0.79 | 154 | empty |
| 2 | 839 | 0.74 | 0.78 | 99 | empty |
| 3 | 786 | 0.73 | 0.78 | 104 | empty |
| 4 | 1040 | 0.70 | 0.74 | 80 | empty |
| 5 | 566 | 0.68 | 0.78 | 55 | empty |
Interfaces
6 interfaces between chains.
- E–F · 2184 Ų buried · 18 hydrogen bonds · protein-protein
- A–F · 2143 Ų buried · 15 hydrogen bonds · protein-protein
- D–E · 2137 Ų buried · 17 hydrogen bonds · protein-protein
- A–B · 1948 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 1910 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 7SEF · Structure of E. coli LetB delta (Ring6) mutant, Ring 1 in the open state (Model 2, Rings… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A769F599
- Elsewhere: RCSB PDB 7SEF · PDBe 7SEF · UniProt A0A769F599
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