MolNFT v1 · #187413 · protein + RNA
TRNA-like structure from brome mosaic virus bound to tyrosyl-tRNA synthetase from phaseolus vulgaris. conformation: bound state 2.
7SCQ · Tyrosine--tRNA ligase: “TRNA-like structure from brome mosaic virus bound to tyrosyl-tRNA synthetase from phaseolus vulgaris.…”. Electron microscopy, 13 pockets (best druggability 0.82). MolNFT v1 #187413 on GenesisL1: 3D structure…
- PDB
- 7SCQ
- Type
- protein + RNA
- Length
- 867 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine--tRNA ligase; TRNA-like structure from brome mosaic virus RNA 3.
- EC
- 6.1.1.1
- UniProt
- V7CJ18
- Pockets
- 13 · best druggability 0.82
Structure
electron microscopy · 2 distinct chains · 57% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Tyrosine--tRNA ligase (EC 6.1.1.1) | protein | 349 | 57% helix, 11% strand | V7CJ18 |
| C | TRNA-like structure from brome mosaic virus RNA 3. | rna | 169 | — | — |
Pockets
13 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 457 | 0.82 | 0.89 | 45 | empty |
| 2 | 481 | 0.79 | 0.86 | 51 | empty |
| 3 | 800 | 0.74 | 0.80 | 35 | empty |
| 4 | 134 | 0.72 | 0.91 | 31 | empty |
| 5 | 862 | 0.71 | 0.77 | 49 | empty |
Interfaces
3 interfaces between chains.
- A–C · 2494 Ų buried · 110 hydrogen bonds · protein-nucleic
- A–B · 973 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 401 Ų buried · 7 hydrogen bonds · protein-nucleic
Compared structures
- 7SCQ · tRNA-like Structure from Brome Mosaic Virus Bound to Tyrosyl-tRNA Synthetase from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt V7CJ18
- Elsewhere: RCSB PDB 7SCQ · PDBe 7SCQ · UniProt V7CJ18
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.