MolNFT v1 · #187408 · protein
AM0627 metallopeptidase from akkermansia muciniphila
7SCI · Peptidase M60 domain-containing protein: “AM0627 metallopeptidase from akkermansia muciniphila”. X-ray diffraction, 2 ligands (ZN, CL), 2 pockets (best druggability 0.38). MolNFT v1 #187408 on GenesisL1: 3D structure, binding sites…
- PDB
- 7SCI
- Type
- protein
- Length
- 487 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptidase M60 domain-containing protein
- UniProt
- B2UPI7
- Ligands
- ZN, CL
- Pockets
- 2 · best druggability 0.38
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peptidase M60 domain-containing protein | protein | 487 | 40% helix, 19% strand | B2UPI7 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
- CL · Chloride ion · ion · chains A
- FMT · Formic acid · additive · 8 copies · chains A
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 103 | 0.38 | 0.76 | 19 | PGE |
| 2 | 94 | 0.30 | 0.72 | 19 | empty |
Compared structures
- 7SCI · AM0627 metallopeptidase from Akkermansia muciniphila · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2UPI7
- Elsewhere: RCSB PDB 7SCI · PDBe 7SCI · UniProt B2UPI7
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