MolNFT v1 · #18740 · DNA

Solution structure of an O6-[4-oxo-4-(3-PYRIDYL)BUTYL]GUANINE adduct in an 11MER DNA duplex

1PYJ · 5'-D(*CP*CP*AP*TP*AP*TP*GP*GP*CP*CP*C)-3': “Solution structure of an O6-[4-oxo-4-(3-PYRIDYL)BUTYL]GUANINE adduct in an 11MER DNA duplex”. Solution nmr. MolNFT v1 #18740 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1PYJ
Type: DNA
Length: 22 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 5'-D(*CP*CP*AP*TP*AP*TP*GP*GP*CP*CP*C)-3'; 5'-D*GP*GP*GP*CP*CP*AP*TP*AP*TP*GP*G)-3'

Structure

solution nmr · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	5'-D(CPCPAPTPAPTPGPGPCPCP*C)-3'	dna	11	—	—
B	5'-DGPGPGPCPCPAPTPAPTPGP*G)-3'	dna	11	—	—

Interfaces

1 interface between chains.

A–B · 553 Å² buried · 46 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 1 modified (nucleotide modification).

Compared structures

1PYJ · Solution Structure of an O6-[4-oxo-4-(3-pyridyl)butyl]guanine adduct in an 11mer DNA… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1PYJ · PDBe 1PYJ

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