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MolNFT v1 · #187369 · protein

Structure of gldlm, the proton-powered motor that drives type IX protein secretion and gliding motility in capnocytophaga canimorsus

7SAZ · Gldm: “Structure of gldlm, the proton-powered motor that drives type IX protein secretion and gliding motility in…”. Electron microscopy, 7 pockets (best druggability 0.80). MolNFT v1 #187369 on GenesisL1: 3D structure, binding…

PDB
7SAZ
Type
protein
Length
722 residues
Chains
7
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Gldm; Gldl
UniProt
F9YQB7, F9YQB6
Pockets
7 · best druggability 0.80

Structure

electron microscopy · 7 distinct chains · 71% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGldmprotein21770% helix, 4% strandF9YQB7
BGldmprotein21568% helix, 4% strandF9YQB7
CGldlprotein6170% helix, 0% strandF9YQB6
DGldlprotein5973% helix, 0% strandF9YQB6
EGldlprotein5673% helix, 4% strandF9YQB6
FGldlprotein5772% helix, 4% strandF9YQB6
GGldlprotein5775% helix, 0% strandF9YQB6

Pockets

7 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18490.800.8279empty
24290.800.8870empty
35160.720.8148empty
43410.610.7830empty
52300.570.7929empty

Interfaces

16 interfaces between chains.

  • A–B · 1736 Ų buried · 11 hydrogen bonds · protein-protein
  • A–E · 595 Ų buried · 3 hydrogen bonds · protein-protein
  • D–E · 569 Ų buried · 1 hydrogen bond · protein-protein
  • C–G · 558 Ų buried · 3 hydrogen bonds · protein-protein
  • F–G · 555 Ų buried · 6 hydrogen bonds · protein-protein

Compared structures

  • 7SAZ · Structure of GldLM, the proton-powered motor that drives Type IX protein secretion and… · the same entry in another collection · chain A against A, TM-score 1.00

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