MolNFT v1 · #187308 · protein
Cryo-EM structure of a mammalian peptide transporter (PEPT1/SLC15A1) in nanodisc
7S8U · Solute carrier family 15 member 1: “Cryo-EM structure of a mammalian peptide transporter (PEPT1/SLC15A1) in nanodisc”. Electron microscopy, 3 pockets (best druggability 0.84). MolNFT v1 #187308 on GenesisL1: 3D structure, binding…
- PDB
- 7S8U
- Type
- protein
- Length
- 667 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Solute carrier family 15 member 1
- UniProt
- F6SG69
- Pockets
- 3 · best druggability 0.84
Structure
electron microscopy · 1 distinct chain · 52% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Solute carrier family 15 member 1 | protein | 667 | 52% helix, 13% strand | F6SG69 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1153 | 0.84 | 0.84 | 98 | empty |
| 2 | 762 | 0.72 | 0.78 | 68 | empty |
| 3 | 159 | 0.64 | 0.85 | 32 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7S8U · Cryo-EM structure of a mammalian peptide transporter (PepT1/slc15a1) in nanodisc · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F6SG69
- Elsewhere: RCSB PDB 7S8U · PDBe 7S8U · UniProt F6SG69
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