MolNFT v1 · #187139 · protein
M. xanthus encapsulin enca bound to encb targeting peptide
7S2T: “M. xanthus encapsulin enca bound to encb targeting peptide”. Electron microscopy, 12 pockets (best druggability 0.77). MolNFT v1 #187139 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7S2T
- Type
- protein
- Length
- 850 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Enca; Encb targeting peptide
- UniProt
- Q1D6H4
- Pockets
- 12 · best druggability 0.77
Structure
electron microscopy · 4 distinct chains · 26% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Enca | protein | 275 | 27% helix, 14% strand | Q1D6H4 |
| C, B | Enca | protein | 270 | 28% helix, 20% strand | Q1D6H4 |
| F, G | Encb targeting peptide | protein | 12 | 0% helix, 0% strand | — |
| H | Encb targeting peptide | protein | 11 | 0% helix, 0% strand | — |
Pockets
12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 111 | 0.77 | 0.96 | 25 | empty |
| 2 | 84 | 0.70 | 0.94 | 29 | empty |
| 3 | 64 | 0.65 | 0.93 | 25 | empty |
| 4 | 120 | 0.58 | 0.84 | 22 | empty |
| 5 | 155 | 0.52 | 0.79 | 24 | empty |
Interfaces
7 interfaces between chains.
- A–F · 677 Ų buried · 9 hydrogen bonds · protein-protein
- C–H · 652 Ų buried · 12 hydrogen bonds · protein-protein
- B–G · 629 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 594 Ų buried · 4 hydrogen bonds · protein-protein
- C–B · 233 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7S2T · M. xanthus encapsulin EncA bound to EncB targeting peptide · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1D6H4
- Elsewhere: RCSB PDB 7S2T · PDBe 7S2T · UniProt Q1D6H4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.