MolNFT v1 · #187107 · protein
N-aromatic-substituted indazole derivatives as brain penetrant and orally bioavailable JNK3 inhibitors
7S1N: “N-aromatic-substituted indazole derivatives as brain penetrant and orally bioavailable JNK3 inhibitors”. X-ray diffraction, 1 ligand (86C). MolNFT v1 #187107 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7S1N
- Type
- protein
- Length
- 346 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P53779
- Ligands
- 86C
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 346 | — | P53779 |
Ligands and binding sites
- 86C · 4-[5-(2-chloro-6-fluoroanilino)-6-methyl-1H-pyrazolo[3, 4-b]pyridin-1-yl]-N-(oxetan-3-yl)thiophene-2-carboxamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7S1N · N-Aromatic-Substituted Indazole Derivatives as Brain Penetrant and Orally Bioavailable… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53779
- Elsewhere: RCSB PDB 7S1N · PDBe 7S1N · UniProt P53779
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.