MolNFT v1 · #187081 · protein

Crystal structure of penicillium verruculosum copalyl diphosphate synthase (pvcps) alpha prenyltransferase domain variant, S723Y

7S0H · Terpene synthase: “Crystal structure of penicillium verruculosum copalyl diphosphate synthase (pvcps) alpha prenyltransferase…”. X-ray diffraction, 6 pockets (best druggability 0.81). MolNFT v1 #187081 on GenesisL1: 3D structure…

PDB: 7S0H
Type: protein
Length: 609 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Terpene synthase
UniProt: A0A348FUE1
Pockets: 6 · best druggability 0.81

Structure

x-ray diffraction · 2 distinct chains · 72% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Terpene synthase	protein	304	73% helix, 1% strand	A0A348FUE1
B	Terpene synthase	protein	305	71% helix, 1% strand	A0A348FUE1

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	785	0.81	0.84	68	empty
2	681	0.80	0.85	58	empty
3	68	0.39	0.79	19	empty
4	54	0.38	0.81	16	empty
5	75	0.38	0.78	21	empty

Interfaces

1 interface between chains.

A–B · 2625 Å² buried · 31 hydrogen bonds · protein-protein

Compared structures

7S0H · Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A348FUE1
Elsewhere: RCSB PDB 7S0H · PDBe 7S0H · UniProt A0A348FUE1

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