MolNFT v1 · #186916 · protein
Structure of the human GIGYF2-TNRC6A complex
7RUP · GRB10-interacting gyf protein 2: “Structure of the human GIGYF2-TNRC6A complex”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #186916 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RUP
- Type
- protein
- Length
- 72 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GRB10-interacting gyf protein 2; Trinucleotide repeat-containing gene 6A protein
- UniProt
- Q6Y7W6, Q8NDV7
- Ligands
- SO4
Structure
x-ray diffraction · 2 distinct chains · 25% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GRB10-interacting gyf protein 2 | protein | 63 | 29% helix, 24% strand | Q6Y7W6 |
| B | Trinucleotide repeat-containing gene 6A protein | protein | 9 | 0% helix, 0% strand | Q8NDV7 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 381 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (oxidation).
Compared structures
- 7RUP · Structure of the human GIGYF2-TNRC6A complex · the same entry in another collection · chain A against A, TM-score 1.00
- Q6Y7W6 · AlphaFold monomer V2.0 prediction for GRB10-interacting gyf protein 2 (Q6Y7W6) · a predicted model of the same protein · chain A against A, TM-score 0.87
- Q8NDV7 · AlphaFold monomer V2.0 prediction for trinucleotide repeat-containing gene 6A protein… · a predicted model of the same protein · chain B against A, TM-score 0.36
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6Y7W6
- Every structure of UniProt Q8NDV7
- Elsewhere: RCSB PDB 7RUP · PDBe 7RUP · UniProt Q6Y7W6 · UniProt Q8NDV7
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