MolNFT v1 · #186866 · protein
Crystal structure of group B human rotavirus VP8*
7RSW · Outer capsid protein VP4: “Crystal structure of group B human rotavirus VP8*”. X-ray diffraction, 2 pockets (best druggability 0.54). MolNFT v1 #186866 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RSW
- Type
- protein
- Length
- 254 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Outer capsid protein VP4; Peptide
- UniProt
- H0USR8
- Pockets
- 2 · best druggability 0.54
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Outer capsid protein VP4 | protein | 125 | 7% helix, 44% strand | H0USR8 |
| C | Peptide | protein | 4 | 0% helix, 50% strand | — |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 233 | 0.54 | 0.77 | 27 | empty |
| 2 | 179 | 0.43 | 0.74 | 25 | empty |
Interfaces
2 interfaces between chains.
- B–C · 159 Ų buried · 5 hydrogen bonds · protein-protein
- A–B · 102 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 7RSW · Crystal structure of group B human rotavirus VP8* · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt H0USR8
- Elsewhere: RCSB PDB 7RSW · PDBe 7RSW · UniProt H0USR8
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