MolNFT v1 · #186825 · protein

IDO1 in complex with compound 14

7RRC: “IDO1 in complex with compound 14”. X-ray diffraction, 1 ligand (6RI). MolNFT v1 #186825 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7RRC
Type: protein
Length: 749 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P14902
Ligands: 6RI

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	375	—	P14902
B	—	protein	374	—	P14902

Ligands and binding sites

6RI · N-(4-fluorophenyl)-3-{4-[4-(hydroxymethyl)-6-(trifluoromethyl)pyridin-3-yl]phenyl}oxetane-3-carboxamide · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7RRC · IDO1 in complex with compound 14 · the same entry in another collection · chain A against A, TM-score 1.00
P14902 · AlphaFold monomer V2.0 prediction for indoleamine 2,3-dioxygenase 1 (P14902) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P14902
Elsewhere: RCSB PDB 7RRC · PDBe 7RRC · UniProt P14902

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