MolNFT v1 · #186788 · protein
Crystal structure of human CEACAM1 with gfcc' and abed face
7RPP · Carcinoembryonic antigen-related cell adhesion molecule 1: “Crystal structure of human CEACAM1 with gfcc' and abed face”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #186788 on GenesisL1: 3D structure, binding…
- PDB
- 7RPP
- Type
- protein
- Length
- 321 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carcinoembryonic antigen-related cell adhesion molecule 1
- UniProt
- P13688
- Pockets
- 1 · best druggability 0.37
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Carcinoembryonic antigen-related cell adhesion molecule 1 | protein | 107 | 6% helix, 51% strand | P13688 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 115 | 0.37 | 0.74 | 19 | empty |
Interfaces
3 interfaces between chains.
- B–C · 873 Ų buried · 13 hydrogen bonds · protein-protein
- A–B · 512 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 31 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7RPP · Crystal structure of human CEACAM1 with GFCC' and ABED face · the same entry in another collection · chain A against A, TM-score 1.00
- P13688 · AlphaFold monomer V2.0 prediction for carcinoembryonic antigen- related cell adhesion… · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13688
- Elsewhere: RCSB PDB 7RPP · PDBe 7RPP · UniProt P13688
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