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MolNFT v1 · #186606 · protein

Complex III2 from candida albicans, inz-5 bound

7RJE: “Complex III2 from candida albicans, inz-5 bound”. Electron microscopy, 4 ligands (HEM, ZL5, HEC). MolNFT v1 #186606 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7RJE
Type
protein
Length
3,818 residues
Chains
18
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P0C8L0, A0A1D8PP59, P83782, A0A1D8PHA3, Q5ABS1, A0A1D8PHA2, A0A1D8PJT8, A0A1D8PLP3, A0A1D8PJX3
Ligands
HEM, ZL5, HEC, FES

Structure

electron microscopy · 9 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
K, T—protein384—P0C8L0
A, E—protein417—A0A1D8PP59
B, L—protein364—P83782
D, N—protein243—A0A1D8PHA3
G, P—protein122—Q5ABS1
F, O—protein88—A0A1D8PHA2
H, Q—protein72—A0A1D8PJT8
I, R—protein38—A0A1D8PLP3
C, M—protein181—A0A1D8PJX3

Ligands and binding sites

  • HEM · Protoporphyrin IX containing Fe · ligand · 4 copies · chains K, T
  • ZL5 · 3-[2-fluoro-5-(trifluoromethyl)phenyl]-7-methyl-1-[(2-methyl-2H-tetrazol-5-yl)methyl]-1H-indazole · ligand · 2 copies · chains K, T
  • HEC · Heme C · ligand · 2 copies · chains D, N
  • FES · Fe2/s2 (inorganic) cluster · ligand · 2 copies · chains C, M

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7RJE · Complex III2 from Candida albicans, Inz-5 bound · the same entry in another collection · chain M against M, TM-score 1.00

Analyse

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