MolNFT v1 · #186571 · protein
The structure of bam in MSP1D1 nanodiscs
7RI7 · Outer membrane protein assembly factor bama: “The structure of bam in MSP1D1 nanodiscs”. Electron microscopy, 20 pockets (best druggability 0.88). MolNFT v1 #186571 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RI7
- Type
- protein
- Length
- 1,520 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Outer membrane protein assembly factor bama; Outer membrane protein assembly factor bamb…
- UniProt
- P0A940, A0A507WQ69, W8SZY2, C3SYV7, A0A3L5AP29
- Pockets
- 20 · best druggability 0.88
Structure
electron microscopy · 5 distinct chains · 20% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Outer membrane protein assembly factor bama | protein | 782 | 16% helix, 30% strand | P0A940 |
| B | Outer membrane protein assembly factor bamb | protein | 370 | 0% helix, 30% strand | A0A507WQ69 |
| C | Outer membrane protein assembly factor bamc | protein | 65 | 0% helix, 0% strand | W8SZY2 |
| D | Outer membrane protein assembly factor bamd | protein | 217 | 78% helix, 0% strand | C3SYV7 |
| E | Outer membrane protein assembly factor bame | protein | 86 | 14% helix, 29% strand | A0A3L5AP29 |
Pockets
20 pockets found on a 1 Å grid, 17 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1180 | 0.88 | 0.89 | 123 | empty |
| 2 | 435 | 0.84 | 0.91 | 72 | empty |
| 3 | 268 | 0.82 | 0.94 | 48 | empty |
| 4 | 519 | 0.80 | 0.86 | 62 | empty |
| 5 | 121 | 0.77 | 0.96 | 28 | empty |
Interfaces
6 interfaces between chains.
- C–D · 2059 Ų buried · 26 hydrogen bonds · protein-protein
- A–B · 1038 Ų buried · 14 hydrogen bonds · protein-protein
- A–D · 840 Ų buried · 10 hydrogen bonds · protein-protein
- A–E · 468 Ų buried · 2 hydrogen bonds · protein-protein
- D–E · 354 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A940
- Every structure of UniProt A0A507WQ69
- Every structure of UniProt W8SZY2
- Every structure of UniProt C3SYV7
- Every structure of UniProt A0A3L5AP29
- Elsewhere: RCSB PDB 7RI7 · PDBe 7RI7 · UniProt P0A940 · UniProt A0A507WQ69 · UniProt W8SZY2 · UniProt C3SYV7 · UniProt A0A3L5AP29
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