MolNFT v1 · #186442 · protein + RNA
SARS-cov-2 replication-transcription complex bound to NSP13 helicase - NSP13(2)-rtc - swiveled class
7RE0: “SARS-cov-2 replication-transcription complex bound to NSP13 helicase - NSP13(2)-rtc - swiveled class”. Electron microscopy, 4 ligands (ADP, AF3, ZN). MolNFT v1 #186442 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RE0
- Type
- protein + RNA
- Length
- 2,624 residues
- Chains
- 8
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0DTD1
- Ligands
- ADP, AF3, ZN, MG
Structure
electron microscopy · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 927 | — | P0DTD1 |
| B | — | protein | 186 | — | P0DTD1 |
| C | — | protein | 75 | — | P0DTD1 |
| D | — | protein | 185 | — | P0DTD1 |
| E, F | — | protein | 590 | — | P0DTD1 |
| P | — | rna | 34 | — | — |
| T | — | rna | 37 | — | — |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · 3 copies · chains A, E, F
- AF3 · Aluminum fluoride · ligand · 2 copies · chains E, F
- ZN · Zinc ion · metal · 8 copies · chains A, E, F
- MG · Magnesium ion · metal · 3 copies · chains A, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7RE0 · SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DTD1
- Elsewhere: RCSB PDB 7RE0 · PDBe 7RE0 · UniProt P0DTD1
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