MolNFT v1 · #18644 · protein
Crystal structure of a conserved cbs domain protein TA0289 of unknown function from thermoplasma acidophilum
1PVM · Conserved hypothetical protein TA0289: “Crystal structure of a conserved cbs domain protein TA0289 of unknown function from thermoplasma acidophilum”. X-ray diffraction, 1 ligand (HG), 3 pockets (best druggability 0.79). MolNFT v1…
- PDB
- 1PVM
- Type
- protein
- Length
- 362 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Conserved hypothetical protein TA0289
- UniProt
- Q9HLD9
- Ligands
- HG
- Pockets
- 3 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Conserved hypothetical protein TA0289 | protein | 178 | 33% helix, 27% strand | Q9HLD9 |
| B | Conserved hypothetical protein TA0289 | protein | 184 | 32% helix, 26% strand | Q9HLD9 |
Ligands and binding sites
- HG · Mercury (II) ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 398 | 0.79 | 0.88 | 50 | empty |
| 2 | 101 | 0.48 | 0.81 | 20 | empty |
| 3 | 117 | 0.46 | 0.78 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 1875 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 1PVM · Crystal Structure of a Conserved CBS Domain Protein TA0289 of Unknown Function from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HLD9
- Elsewhere: RCSB PDB 1PVM · PDBe 1PVM · UniProt Q9HLD9
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