GL1X · GenesisL1 explorer

MolNFT v1 · #186287 · protein

Crystal structure of the lnk SH2 domain in complex with an epor PY454 phosphopeptide

7R8X · SH2B adapter protein 3: “Crystal structure of the lnk SH2 domain in complex with an epor PY454 phosphopeptide”. X-ray diffraction. MolNFT v1 #186287 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7R8X
Type
protein
Length
119 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
SH2B adapter protein 3; Epor PY454 phosphopeptide
UniProt
O09039

Structure

x-ray diffraction · 2 distinct chains · 26% helix, 24% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASH2B adapter protein 3protein11128% helix, 26% strandO09039
CEpor PY454 phosphopeptideprotein80% helix, 0% strand—

Interfaces

1 interface between chains.

  • A–C · 607 Ų buried · 13 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide, 1 modified (disulfide, phosphorylation).

Compared structures

  • 7R8X · Crystal Structure of the LNK SH2 Domain in Complex with an EPOR pY454 Phosphopeptide · the same entry in another collection · chain A against A, TM-score 1.00
  • O09039 · AlphaFold monomer V2.0 prediction for SH2B adapter protein 3 (O09039) · a predicted model of the same protein · chain A against A, TM-score 0.96

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