MolNFT v1 · #186250 · protein

Crystal structure of triosephosphate isomerase from candidate division katanobacteria (WWE3) bacterium

7R7M: “Crystal structure of triosephosphate isomerase from candidate division katanobacteria (WWE3) bacterium”. X-ray diffraction, 1 ligand (PO4), 2 pockets (best druggability 0.68). MolNFT v1 #186250 on GenesisL1: 3D structure, binding…

PDB: 7R7M
Type: protein
Length: 432 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Triosephosphate isomerase
EC: 5.3.1.1
UniProt: A0A656PMZ5
Ligands: PO4
Pockets: 2 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Triosephosphate isomerase (EC 5.3.1.1)	protein	216	38% helix, 20% strand	A0A656PMZ5

Ligands and binding sites

PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	258	0.68	0.84	43	empty
2	64	0.50	0.86	24	PO4

Interfaces

1 interface between chains.

A–B · 1607 Å² buried · 33 hydrogen bonds · protein-protein

Compared structures

7R7M · Crystal structure of Triosephosphate isomerase from Candidate division Katanobacteria… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A656PMZ5
Elsewhere: RCSB PDB 7R7M · PDBe 7R7M · UniProt A0A656PMZ5

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