MolNFT v1 · #186165 · protein

Crystal structure of ctx-M-15 G238C/A240 insert mutant apoenzyme

7R3Q · Beta-lactamase: “Crystal structure of ctx-M-15 G238C/A240 insert mutant apoenzyme”. X-ray diffraction, 2 ligands (SO4, CL), 1 pocket (best druggability 0.30). MolNFT v1 #186165 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 7R3Q
Type: protein
Length: 263 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase
EC: 3.5.2.6
UniProt: G3G192
Ligands: SO4, CL
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	263	44% helix, 18% strand	G3G192

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.30	0.75	20	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7R3Q · Crystal structure of CTX-M-15 G238C/A240 insert mutant apoenzyme · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G3G192
Elsewhere: RCSB PDB 7R3Q · PDBe 7R3Q · UniProt G3G192

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.