MolNFT v1 · #186109 · protein
Complex of rice blast (magnaporthe oryzae) effector protein avr-pikf with an engineered hma domain of pikp-1 (pikp-snk-eke) from rice (oryza sativa)
7QZD · Resistance protein pikp-1: “Complex of rice blast (magnaporthe oryzae) effector protein avr-pikf with an engineered hma domain of pikp-1…”. X-ray diffraction, 5 pockets (best druggability 0.50). MolNFT v1 #186109 on GenesisL1: 3D…
- PDB
- 7QZD
- Type
- protein
- Length
- 458 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Resistance protein pikp-1; Avr-pik
- UniProt
- E9KPB5, A0A219T3Y8
- Pockets
- 5 · best druggability 0.50
Structure
x-ray diffraction · 5 distinct chains · 24% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Resistance protein pikp-1 | protein | 73 | 33% helix, 40% strand | E9KPB5 |
| B | Resistance protein pikp-1 | protein | 76 | 28% helix, 37% strand | E9KPB5 |
| C, G | Avr-pik | protein | 82 | 4% helix, 45% strand | A0A219T3Y8 |
| E | Resistance protein pikp-1 | protein | 71 | 31% helix, 38% strand | E9KPB5 |
| F | Resistance protein pikp-1 | protein | 74 | 28% helix, 38% strand | E9KPB5 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 103 | 0.50 | 0.81 | 28 | empty |
| 2 | 72 | 0.47 | 0.83 | 18 | empty |
| 3 | 96 | 0.36 | 0.75 | 16 | empty |
| 4 | 60 | 0.31 | 0.75 | 13 | empty |
| 5 | 71 | 0.31 | 0.74 | 17 | empty |
Interfaces
8 interfaces between chains.
- B–C · 1083 Ų buried · 20 hydrogen bonds · protein-protein
- F–G · 1064 Ų buried · 18 hydrogen bonds · protein-protein
- A–B · 543 Ų buried · 15 hydrogen bonds · protein-protein
- E–F · 531 Ų buried · 9 hydrogen bonds · protein-protein
- C–E · 384 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 7QZD · Complex of rice blast (Magnaporthe oryzae) effector protein AVR-PikF with an engineered… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E9KPB5
- Every structure of UniProt A0A219T3Y8
- Elsewhere: RCSB PDB 7QZD · PDBe 7QZD · UniProt E9KPB5 · UniProt A0A219T3Y8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.