MolNFT v1 · #186072 · protein

Crystal structure of the DNA-binding protein ddrc from deinococcus radiodurans

7QVB · DNA damage response protein C: “Crystal structure of the DNA-binding protein ddrc from deinococcus radiodurans”. X-ray diffraction, 1 ligand (SO4), 6 pockets (best druggability 0.56). MolNFT v1 #186072 on GenesisL1: 3D structure…

PDB: 7QVB
Type: protein
Length: 442 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA damage response protein C
Ligands: SO4
Pockets: 6 · best druggability 0.56

Structure

x-ray diffraction · 2 distinct chains · 63% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA damage response protein C	protein	214	64% helix, 10% strand	—
B	DNA damage response protein C	protein	228	62% helix, 10% strand	—

Ligands and binding sites

SO4 · Sulfate ion · ion · 14 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	278	0.56	0.77	34	SO4
2	282	0.53	0.75	35	empty
3	134	0.44	0.77	22	SO4
4	61	0.38	0.79	13	empty
5	52	0.36	0.79	12	SO4

Interfaces

1 interface between chains.

A–B · 3405 Å² buried · 24 hydrogen bonds · protein-protein

Compared structures

7QVB · Crystal structure of the DNA-binding protein DdrC from Deinococcus radiodurans · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7QVB · PDBe 7QVB

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.