MolNFT v1 · #186021 · protein

Crystal structure of nhl domain of TRIM3

7QRW · Isoform 4 of tripartite motif-containing protein 3: “Crystal structure of nhl domain of TRIM3”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.66). MolNFT v1 #186021 on GenesisL1: 3D structure, binding sites and…

PDB: 7QRW
Type: protein
Length: 276 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Isoform 4 of tripartite motif-containing protein 3
UniProt: O75382
Ligands: SO4
Pockets: 1 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 1% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Isoform 4 of tripartite motif-containing protein 3	protein	276	1% helix, 50% strand	O75382

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	370	0.66	0.80	37	empty

Compared structures

7QRW · Crystal structure of NHL domain of TRIM3 · the same entry in another collection · chain A against A, TM-score 1.00
O75382 · AlphaFold monomer V2.0 prediction for tripartite motif-containing protein 3 (O75382) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O75382
Elsewhere: RCSB PDB 7QRW · PDBe 7QRW · UniProt O75382

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