MolNFT v1 · #185995 · protein
Crystal structure of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K2C) bound to an allosteric inhibitor and AMP-pnp
7QPN: “Crystal structure of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K2C) bound to an allosteric inhibitor…”. X-ray diffraction, 2 ligands (DVF, ANP). MolNFT v1 #185995 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7QPN
- Type
- protein
- Length
- 630 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Ligands
- DVF, ANP
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 317 | — | — |
| B | — | protein | 313 | — | — |
Ligands and binding sites
- DVF · 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine · ligand · 2 copies · chains A, B
- ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7QPN · Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7QPN · PDBe 7QPN
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