MolNFT v1 · #185920 · protein

Endothiapepsin in 10% dmso at 298 K

7QM0: “Endothiapepsin in 10% dmso at 298 K”. X-ray diffraction, 1 pocket (best druggability 0.59). MolNFT v1 #185920 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7QM0
Type: protein
Length: 330 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endothiapepsin
EC: 3.4.23.22
UniProt: P11838
Pockets: 1 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endothiapepsin (EC 3.4.23.22)	protein	330	11% helix, 46% strand	P11838

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	325	0.59	0.77	39	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7QM0 · Endothiapepsin in 10% DMSO at 298 K · the same entry in another collection · chain A against A, TM-score 1.00
P11838 · AlphaFold monomer V2.0 prediction for endothiapepsin (P11838) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P11838
Elsewhere: RCSB PDB 7QM0 · PDBe 7QM0 · UniProt P11838

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