MolNFT v1 · #185807 · protein
IRAK4 in complex with inhibitor
7QG1: “IRAK4 in complex with inhibitor”. X-ray diffraction, 1 ligand (B8I). MolNFT v1 #185807 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7QG1
- Type
- protein
- Length
- 548 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9NWZ3
- Ligands
- B8I
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 266 | — | Q9NWZ3 |
| B | — | protein | 282 | — | Q9NWZ3 |
Ligands and binding sites
- B8I · methyl 4-[4-[[6-(cyanomethyl)-2-[(1-methylpyrazol-4-yl)amino]-5-oxidanylidene-pyrido[4,3-d]pyrimidin-4-yl]amino]cyclohexyl]piperazine-1-carboxylate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7QG1 · IRAK4 in complex with inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NWZ3
- Elsewhere: RCSB PDB 7QG1 · PDBe 7QG1 · UniProt Q9NWZ3
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