GL1X · GenesisL1 explorer

MolNFT v1 · #185433 · protein

Crystal structure of the folded domain of porn

7PVH · Por secretion system protein PORN/GLDN: “Crystal structure of the folded domain of porn”. X-ray diffraction, 4 pockets (best druggability 0.74). MolNFT v1 #185433 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7PVH
Type
protein
Length
384 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Por secretion system protein PORN/GLDN
UniProt
B2RLE7
Pockets
4 · best druggability 0.74

Structure

x-ray diffraction · 2 distinct chains · 25% helix, 31% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APor secretion system protein PORN/GLDNprotein19524% helix, 31% strandB2RLE7
BPor secretion system protein PORN/GLDNprotein18926% helix, 31% strandB2RLE7

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12220.740.8937empty
2700.340.7618empty
3520.290.7514empty
4510.280.7515empty

Interfaces

1 interface between chains.

  • A–B · 1403 Ų buried · 28 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

  • 7PVH · Crystal structure of the folded domain of PorN · the same entry in another collection · chain A against A, TM-score 1.00

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