MolNFT v1 · #184971 · protein

Phage resistance protein

7P9M · DUF262 domain-containing protein: “Phage resistance protein”. X-ray diffraction, 2 ligands (SO4, CL), 16 pockets (best druggability 0.68). MolNFT v1 #184971 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7P9M
Type: protein
Length: 1,120 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DUF262 domain-containing protein
UniProt: B7L3S9
Ligands: SO4, CL
Pockets: 16 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 49% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DUF262 domain-containing protein	protein	563	48% helix, 9% strand	B7L3S9
B	DUF262 domain-containing protein	protein	557	50% helix, 10% strand	B7L3S9

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains A, B
CL · Chloride ion · ion · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

16 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	637	0.68	0.76	58	SO4
2	121	0.64	0.87	17	empty
3	282	0.56	0.76	32	SO4
4	203	0.53	0.78	29	empty
5	168	0.45	0.75	23	empty

Interfaces

1 interface between chains.

A–B · 2666 Å² buried · 30 hydrogen bonds · protein-protein

Compared structures

7P9M · BrxU, GmrSD-family Type IV restriction enzyme · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B7L3S9
Elsewhere: RCSB PDB 7P9M · PDBe 7P9M · UniProt B7L3S9

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