MolNFT v1 · #18473 · protein

Crystal structure of znua

1PQ4 · Periplasmic binding protein component of an ABC type zinc…: “Crystal structure of znua”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.60). MolNFT v1 #18473 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 1PQ4
Type: protein
Length: 519 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Periplasmic binding protein component of an ABC type zinc uptake transporter
UniProt: P73085
Ligands: ZN
Pockets: 2 · best druggability 0.60

Structure

x-ray diffraction · 2 distinct chains · 50% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Periplasmic binding protein component of an ABC type zinc uptake transporter	protein	255	50% helix, 16% strand	P73085
B	Periplasmic binding protein component of an ABC type zinc uptake transporter	protein	264	50% helix, 15% strand	P73085

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	441	0.60	0.75	54	empty
2	56	0.27	0.73	19	empty

Interfaces

1 interface between chains.

A–B · 690 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

1PQ4 · Crystal structure of ZnuA · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P73085
Elsewhere: RCSB PDB 1PQ4 · PDBe 1PQ4 · UniProt P73085

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