MolNFT v1 · #184677 · protein
E.COLI'S putrescine receptor variant POTF/D (4JDF) with mutations E39D Y87S in complex with spermidine
7OYS · Putrescine-binding periplasmic protein: “E.COLI'S putrescine receptor variant POTF/D (4JDF) with mutations E39D Y87S in complex with spermidine”. X-ray diffraction, 2 ligands (SPD, CL), 2 pockets (best druggability 0.69). MolNFT v1…
- PDB
- 7OYS
- Type
- protein
- Length
- 342 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putrescine-binding periplasmic protein
- UniProt
- A0A6S5NLK9
- Ligands
- SPD, CL
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putrescine-binding periplasmic protein | protein | 342 | 49% helix, 19% strand | A0A6S5NLK9 |
Ligands and binding sites
- SPD · Spermidine · ligand · chains A
- CL · Chloride ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 15 copies · chains A
- GOL · Glycerol · additive · 2 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 351 | 0.69 | 0.82 | 38 | SPD, CL |
| 2 | 135 | 0.47 | 0.78 | 23 | EDO, GOL |
Compared structures
- 7OYS · E.coli's putrescine receptor variant PotF/D (4JDF) with mutations E39D Y87S in complex… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A6S5NLK9
- Elsewhere: RCSB PDB 7OYS · PDBe 7OYS · UniProt A0A6S5NLK9
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