MolNFT v1 · #184649 · protein
Crystal structure of human spermine oxidase
7OXL · Spermine OXIDASE,SPERMINE OXIDASE,SPERMINE oxidase: “Crystal structure of human spermine oxidase”. X-ray diffraction, 2 ligands (6YU, CL), 3 pockets (best druggability 0.80). MolNFT v1 #184649 on GenesisL1: 3D structure, binding…
- PDB
- 7OXL
- Type
- protein
- Length
- 442 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Spermine OXIDASE,SPERMINE OXIDASE,SPERMINE oxidase
- EC
- 1.5.3.16
- UniProt
- Q9NWM0
- Ligands
- 6YU, CL
- Pockets
- 3 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Spermine OXIDASE,SPERMINE OXIDASE,SPERMINE oxidase (EC 1.5.3.16) | protein | 442 | 43% helix, 20% strand | Q9NWM0 |
Ligands and binding sites
- 6YU · FAD-MDL72527 adduct · ligand · chains A
- CL · Chloride ion · ion · 2 copies · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 554 | 0.80 | 0.86 | 69 | 6YU |
| 2 | 450 | 0.61 | 0.76 | 40 | CL |
| 3 | 225 | 0.55 | 0.78 | 35 | MPD |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NWM0
- Elsewhere: RCSB PDB 7OXL · PDBe 7OXL · UniProt Q9NWM0
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