MolNFT v1 · #184648 · protein

Ttslyd with W4K pseudo-wild-type S2 peptide

7OXK · Peptidyl-prolyl cis-trans isomerase: “Ttslyd with W4K pseudo-wild-type S2 peptide”. X-ray diffraction, 1 pocket (best druggability 0.43). MolNFT v1 #184648 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7OXK
Type: protein
Length: 175 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Peptidyl-prolyl cis-trans isomerase; 30S ribosomal protein S2
EC: 5.2.1.8
UniProt: Q5SLE7, P0A7V0
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 3 distinct chains · 11% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)	protein	150	13% helix, 45% strand	Q5SLE7
B	30S ribosomal protein S2	protein	14	0% helix, 7% strand	P0A7V0
C	30S ribosomal protein S2	protein	11	0% helix, 18% strand	P0A7V0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.43	0.77	16	empty

Interfaces

3 interfaces between chains.

A–B · 862 Å² buried · 9 hydrogen bonds · protein-protein
A–C · 761 Å² buried · 9 hydrogen bonds · protein-protein
B–C · 111 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

7OXK · ttSlyD with W4K pseudo-wild-type S2 peptide · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SLE7
Every structure of UniProt P0A7V0
Elsewhere: RCSB PDB 7OXK · PDBe 7OXK · UniProt Q5SLE7 · UniProt P0A7V0

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