MolNFT v1 · #184551 · protein
Metabolon-embedded pyruvate dehydrogenase complex E2 core at near- atomic resolution
7OTT · Acetyltransferase component of pyruvate dehydrogenase…: “Metabolon-embedded pyruvate dehydrogenase complex E2 core at near- atomic resolution”. Electron microscopy, 1 pocket (best druggability 0.50). MolNFT v1 #184551 on GenesisL1…
- PDB
- 7OTT
- Type
- protein
- Length
- 209 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acetyltransferase component of pyruvate dehydrogenase complex
- EC
- 2.3.1.12
- UniProt
- G0S4X6
- Pockets
- 1 · best druggability 0.50
Structure
electron microscopy · 1 distinct chain · 32% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) | protein | 209 | 32% helix, 27% strand | G0S4X6 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 183 | 0.50 | 0.77 | 31 | empty |
Compared structures
- 7OTT · Metabolon-embedded pyruvate dehydrogenase complex E2 core at near-atomic resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0S4X6
- Elsewhere: RCSB PDB 7OTT · PDBe 7OTT · UniProt G0S4X6
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