MolNFT v1 · #184408 · protein
Cryo-EM structure of P5B-ATPase E2PINHIBIT
7OP8 · Cation-transporting ATPase: “Cryo-EM structure of P5B-ATPase E2PINHIBIT”. Electron microscopy, 2 ligands (BEF, MG), 18 pockets (best druggability 0.83). MolNFT v1 #184408 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OP8
- Type
- protein
- Length
- 1,118 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cation-transporting ATPase
- EC
- 7.2.2.-
- UniProt
- G0S7G9
- Ligands
- BEF, MG
- Pockets
- 18 · best druggability 0.83
Structure
electron microscopy · 1 distinct chain · 38% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cation-transporting ATPase (EC 7.2.2.-) | protein | 1118 | 38% helix, 16% strand | G0S7G9 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
18 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1148 | 0.83 | 0.84 | 114 | empty |
| 2 | 464 | 0.66 | 0.78 | 65 | empty |
| 3 | 217 | 0.62 | 0.82 | 24 | empty |
| 4 | 171 | 0.60 | 0.82 | 33 | empty |
| 5 | 57 | 0.59 | 0.92 | 17 | empty |
Compared structures
- 7OP8 · Cryo-EM structure of P5B-ATPase E2Pinhibit · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0S7G9
- Elsewhere: RCSB PDB 7OP8 · PDBe 7OP8 · UniProt G0S7G9
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