MolNFT v1 · #184314 · protein
Mertk kinase domain with type 1.5 inhibitor containing a di-methyl, cyano pyrazole group
7OLV: “Mertk kinase domain with type 1.5 inhibitor containing a di-methyl, cyano pyrazole group”. X-ray diffraction, 2 ligands (VK2, CL). MolNFT v1 #184314 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OLV
- Type
- protein
- Length
- 273 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q12866
- Ligands
- VK2, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 273 | — | Q12866 |
Ligands and binding sites
- VK2 · 4-[4-[5-[imidazo[1,2-a]pyridin-6-ylmethyl(methyl) amino]-1,3,4-oxadiazol-2-yl]-3-methyl-phenyl]-2,5-dimethyl-pyrazole-3-carbonitrile · ligand · chains A
- CL · Chloride ion · ion · 4 copies · chains A
- DMS · Dimethyl sulfoxide · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OLV · MerTK kinase domain with type 1.5 inhibitor containing a di-methyl, cyano pyrazole group · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12866
- Elsewhere: RCSB PDB 7OLV · PDBe 7OLV · UniProt Q12866
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