MolNFT v1 · #184217 · protein + RNA
Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex
7OI3: “Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex”. Electron microscopy, 4 pockets (best druggability 0.31). MolNFT v1 #184217 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OI3
- Type
- protein + RNA
- Length
- 400 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cetacean morbillivirus nucleoprotein; Poly-a 6-mer
- UniProt
- A0A1I9RYK9
- Pockets
- 4 · best druggability 0.31
Structure
electron microscopy · 2 distinct chains · 54% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | Cetacean morbillivirus nucleoprotein | protein | 394 | 54% helix, 6% strand | A0A1I9RYK9 |
| B | Poly-a 6-mer | rna | 6 | — | — |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.31 | 0.75 | 14 | empty |
| 2 | 60 | 0.30 | 0.75 | 17 | empty |
| 3 | 56 | 0.29 | 0.75 | 14 | empty |
| 4 | 59 | 0.29 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- E–B · 978 Ų buried · 27 hydrogen bonds · protein-nucleic
Compared structures
- 7OI3 · Cryo-EM structure of the Cetacean morbillivirus nucleoprotein-RNA complex · the same entry in another collection · chain E against E, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1I9RYK9
- Elsewhere: RCSB PDB 7OI3 · PDBe 7OI3 · UniProt A0A1I9RYK9
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