MolNFT v1 · #18404 · protein
Crystal structure of ferric citrate transporter feca in complex with iron-free citrate
1PO0 · IRON(III) dicitrate transport protein feca precursor: “Crystal structure of ferric citrate transporter feca in complex with iron-free citrate”. X-ray diffraction, 6 pockets (best druggability 0.85). MolNFT v1 #18404 on GenesisL1: 3D…
- PDB
- 1PO0
- Type
- protein
- Length
- 661 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- IRON(III) dicitrate transport protein feca precursor
- UniProt
- P13036
- Pockets
- 6 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | IRON(III) dicitrate transport protein feca precursor | protein | 661 | 7% helix, 54% strand | P13036 |
Ligands and binding sites
- FLC · Citrate anion · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 324 | 0.85 | 0.95 | 66 | empty |
| 2 | 588 | 0.76 | 0.83 | 72 | FLC |
| 3 | 344 | 0.72 | 0.85 | 40 | empty |
| 4 | 383 | 0.71 | 0.83 | 36 | empty |
| 5 | 384 | 0.70 | 0.82 | 43 | empty |
Compared structures
- 1PO0 · Crystal structure of ferric citrate transporter FecA in complex with iron-free citrate · the same entry in another collection · chain A against A, TM-score 1.00
- P13036 · AlphaFold monomer V2.0 prediction for FE(3+) dicitrate transport protein feca (P13036) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13036
- Elsewhere: RCSB PDB 1PO0 · PDBe 1PO0 · UniProt P13036
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