MolNFT v1 · #183982 · protein
Escherichia COLI ftsy in complex with pppgpp
7O9H · Signal recognition particle receptor ftsy: “Escherichia COLI ftsy in complex with pppgpp”. X-ray diffraction, 1 ligand (C1Z), 5 pockets (best druggability 0.77). MolNFT v1 #183982 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7O9H
- Type
- protein
- Length
- 605 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Signal recognition particle receptor ftsy
- UniProt
- A0A7D5IKJ2
- Ligands
- C1Z
- Pockets
- 5 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 54% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Signal recognition particle receptor ftsy | protein | 302 | 53% helix, 14% strand | A0A7D5IKJ2 |
| B | Signal recognition particle receptor ftsy | protein | 303 | 54% helix, 13% strand | A0A7D5IKJ2 |
Ligands and binding sites
- C1Z · Guanosine 3'-diphosphate 5'-triphosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 787 | 0.77 | 0.81 | 57 | empty |
| 2 | 89 | 0.41 | 0.78 | 24 | C1Z |
| 3 | 60 | 0.40 | 0.81 | 19 | empty |
| 4 | 71 | 0.34 | 0.76 | 17 | empty |
| 5 | 59 | 0.29 | 0.74 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 744 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 7O9H · Escherichia coli FtsY in complex with pppGpp · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A7D5IKJ2
- Elsewhere: RCSB PDB 7O9H · PDBe 7O9H · UniProt A0A7D5IKJ2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.