MolNFT v1 · #183946 · protein
Cystal structure of zymogen granule protein 16 (ZG16)
7O88 · Zymogen granule membrane protein 16: “Cystal structure of zymogen granule protein 16 (ZG16)”. X-ray diffraction, 1 pocket (best druggability 0.32). MolNFT v1 #183946 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7O88
- Type
- protein
- Length
- 283 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Zymogen granule membrane protein 16
- UniProt
- O60844
- Pockets
- 1 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 4% helix, 57% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zymogen granule membrane protein 16 | protein | 142 | 4% helix, 57% strand | O60844 |
| B | Zymogen granule membrane protein 16 | protein | 141 | 4% helix, 57% strand | O60844 |
Ligands and binding sites
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.32 | 0.74 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 397 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 7O88 · Cystal structure of Zymogen Granule Protein 16 (ZG16) · the same entry in another collection · chain A against A, TM-score 1.00
- O60844 · AlphaFold monomer V2.0 prediction for zymogen granule membrane protein 16 (O60844) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60844
- Elsewhere: RCSB PDB 7O88 · PDBe 7O88 · UniProt O60844
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