MolNFT v1 · #183732 · DNA

Hybrid-2R quadruplex-duplex with (-P-P-L) topology and 3 syn residues

7O1H · DNA (31-mer): “Hybrid-2R quadruplex-duplex with (-P-P-L) topology and 3 syn residues”. Solution nmr, 1 pocket (best druggability 0.31). MolNFT v1 #183732 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7O1H
Type: DNA
Length: 31 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA (31-mer)
Pockets: 1 · best druggability 0.31

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA (31-mer)	dna	31	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	88	0.31	0.73	12	empty

Modifications

Observed in the structure: 3 modified (nucleotide modification).

Compared structures

7O1H · Hybrid-2R quadruplex-duplex with (-p-p-l) topology and 3 syn residues · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7O1H · PDBe 7O1H

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